Friday, March 15, 2019

Know more about Osteoporosis


  • What is osteoporosis?

  Osteoporosis is a general skeletal disorder that affects mainly women after menopause. it is a decrease in bone mass and a deterioration of bone's microarchitecture.
  • How does a bone work?

  Bone is a living tissue that is continually renewed thanks to the coupled functioning of two types of bone cells:
- Osteoclasts, which destroy the old bone
- Osteoblasts, who make a new bone.
  These activities of destruction and formation are normally balanced by a precise regulation, under the influence of many factors (vitamin D, sex hormones, thyroid hormones, etc.). When the formation of bone does not compensate for its destruction, the bone density decreases, it is osteoporosis.
  • Osteoporosis, a silent disease :

  Osteoporosis is a silent and painless disease. The pain appears only at the time of a complication that can reveal the disease: fractures. Three types of fractures are the most common:
- Vertebral fractures.
- The fracture of the hip.
- Wrist fracture.
  • What are the causes ?

   Osteoporosis can have several causes, depending on whether it is called "primitive" or "secondary" when it is the consequence of another disease.
  1. Factors of so-called "primitive" osteoporosis:

- Genetic factors
- Juvenile (up to the age of 25)
- Pregnancy
- Menopause
- Aging in humans (after 70 years)

       2. Factors of secondary osteoporosis:

- Prolonged treatment with high doses of cortisone
- Inflammatory rheumatism (rheumatoid arthritis, spondyloarthritis, juvenile chronic arthritis)
- Endocrine diseases (thyroid diseases, insufficient sexual glands)
- Digestive diseases (severe liver disease, chronic bowel disease)
- Other causes (anorexia nervosa, alcohol-tobacco poisoning, severe malnutrition, prolonged immobilization, chronic leakage of calcium in the urine, tumoral diseases, organ transplants, severe chronic renal insufficiency).
  • How to recognize it?

In the absence of a major fracture (vertebra, hip, arm, ribs, etc.) following a low-intensity trauma, only bone densitometry can confirm or invalidate the presence of the disease: this key examination measures with Precise bone mineral density. The lower the measured value, the more advanced the osteoporosis.

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